Joint Mobility and ComfortNOW Vegetarian Glucosamine '1000' is a well-known joint support ingredient that is vegetarian/vegan friendly and not shellfish-derived. Glucosamine is an essential building block for the formation of glycosaminoglycans (GAGs) and proteoglycans, the main components of cartilage tissue. These compounds attract water to form a joint cushion, providing lubrication and shock absorption.